THE HORMONE BLOODWORK FIELD GUIDEEditorial standards →

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Total T, free T and SHBG

How binding proteins and testing methods change what you see.

Three numbers, different jobs

Total T includes bound and unbound hormone. Free T is the unbound fraction. SHBG binds testosterone and can help explain why total and free T point in different directions.

Read the method before the range

Use the performing lab’s interval and record the collection timing. A harmonized research interval of 264 to 916 ng/dL came from healthy nonobese men aged 19 to 39. Your report may use another assay or reference population.

Compare like with like

Measured free T and calculated free T can differ. Keep your calculation method, units and input assays consistent when you compare results over time.

Sources

Bring the right question to your next draw.

Check the marker, testing method and current price before ordering.

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